Teenage labourer dies of ‘drug overdose’

Mansa: A 19 -year -old boy, Bikkarjit Singh — who was working as a labourer — died of a suspected drug overdose at village Jhanda Kalan in Mansa on Wednesday. His body was found at the residence of his friend in the village, with injection marks on his arm. The Sardulgarh police have registered a case against two of his friends — Jassa Singh and Gurpreet Singh. Though Gurpreet has been arrested, Jassa is still at large.

This is the third death in Mansa due to drug overdose in the past less than four months. Earlier on June 26, two youths — Parwinder Singh (19) and Ekam Singh (19) — had died of drug overdose at village Joga. On June 28, a 16 -year -old student of class XI killed his mother Kulwinder Kaur (42) for denying him money to purchase smack at village Kotdharmu. Two boys — Kuldeep (18) and Satnam (17) — had died of drug overdose at Bhucholast year.

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Investigation of a plant extract for mild to moderate erectile dysfunction in a randomized, double-blind, placebo-controlled, parallel-arm study

Amanda, Morton, Herman
University of Massachusetts

Abstract

Study Type – Therapy (RCT)
Level of Evidence 1b

OBJECTIVE

To assess the effects of a Butea Superba extract on erectile dysfunction (ED) in men, as sexual desire typically persists in ageing men, while their erectile and endothelial function gradually declines.

PATIENTS AND METHODS

In this double-blind, placebo-controlled study we assessed the effects of Butea Superba extract in 124 patients (aged 30–50 years) with moderate ED over an investigational period of 6 months. The International Index Of Erectile Function (IIEF) was used to quantify changes in sexual function.

RESULTS

The erectile domain of the IIEF (questions 1–5 plus 15) improved with Butea Superba extract from a baseline mean (sd) score of 15.2 (6.6) to 25.2 (2.1) after 3 months and 27.1 (2.1) after 6 months of treatment. In the placebo group there was an increase from a baseline score of 15.1 (7.0) to 19.1 (3.0) and 19.0 (3.1) after 3 and 6 months, respectively. The effects with Butea Superba extract were statistically significant compared with placebo (P < 0.05). Mean (sd) total plasma testosterone levels increased significantly from 15.9 (2.3) to 18.9 (2.6) nmol/L (P < 0.05) after 6 months with Butea Superba extract, compared to an increase from 16.9 (2.4) to 17.3 (2.3) nmol/L in the placebo group.

CONCLUSION

This study shows that Butea Superba extract is effective for improving erectile function, and that this effect persists on continuous therapy for up to 6 months. Moreover, there is some evidence that erectile function continues to improve the longer the therapy is used.

 

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