Love drugs that work


Version 3.0, August 2004

Love drugs, of course, have occupied medical research before there has been the term "medical research".

For hardly any medication were the rich and powerful (mostly men) throughout the ages as willing to spend substantial amounts of money as they were for drugs that were sold to them with the promise of returning virility or providing that extra prowess.

In some ways the world hasn't changed. In proportion to production costs and considering that it's a mass-market product, Viagra was, when it was introduced to the market, probably the most expensive medication around.

And rightly so. The incapacity to have a satisfying sex life is such a tremendous loss of quality of life that a good number of men would chose the latter if given the option to either loose a leg or that organ which, again rightfully, is called vital.

There are hundreds of substances, both herbal and synthetic, which can ruin a man's capability to have an erection. And there are only a few substances that actually enhance male sexual function and could treat impotence.

However, we have to be aware that male sexuality is comprised of two very distinct, and different, components: sexual plumbing (concerned with the necessities for achieving an erection), and sexual wiring (the involvement of the nervous system, including the brain).

The two functions are distinct, and in a way, they are contrary to each other. There are a good number of substances that are good for the one, and bad for the other aspect of sexuality. Kokain, for example, can enhance sexual desire, while at the same time obstructing penile function by causing a shrinkage of the organ.

Viagra, on the other hand, is good for erections, but if one ingests more than one needs, it will weaken orgasm. The pros and cons of Viagra are meanwhile well known to many men.

Very few substances are good for both, erections and libido. Yohimbe, the bark, or yohimbine, the active ingredient, which has been extracted and is sold as pharmaceutical, facilitate erections by blocking adrenaline from abdominal and pelvic receptors, and enhance libido by increasing adrenaline effect on the brain. However, there is no question that the side effects of yohimbe and yohimbine are a serious deterrent. The adrenaline blocked from the abdominal and pelvic areas also causes heart palpitations and sleeplessness, and both these effects are not supportive of general health.

While the discovery of the use phosphodiesterase inhibitors such as Viagra for erectile function has been a definite achievement, the bigger challenge is to develop a medication that can enhance libido. The impact that such a medication could have on the behavioral patterns of young and aging men around the world is substantial. Such a medication could have the effect of a large number of men making far-reaching changes to their lifestyles in that they might become libido-driven to a far greater degree than what currently is the case.

There are basically two pathways for the enhancement of libido: a hormonal route via testosterone and a neurotransmitter route via dopamine. While the outright application of testosterone may have a clear anabolic effect, exogenous testosterone has the potential to lower both libido and fertility in men, not just to raise it. What effect it will have will depend on baseline values, set points, and dosages. A much more promising route is to support the body's own testosterone synthesis with tongkat ali or injection of human chorionic gonadotropin (which is extracted from the urine of pregnant women and therefore rather expensive).

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Breast implant

A breast implant is a prosthesis used to enlarge the size of a woman's breasts (known as breast augmentation, breast enlargement, mammoplasty enlargement, augmentation mammoplasty or the common slang term boob job) for cosmetic reasons; to reconstruct the breast (e.g. after a mastectomy; or to correct genetic deformities), or as an aspect of male-to-female sex reassignment surgery. According to the American Society of Plastic Surgeons, breast augmentation is the most commonly performed cosmetic surgical procedure in the United States. In 2006, 329,000 breast augmentation procedures were performed in the U.S.[1]

There are two primary types of breast implants: saline-filled and silicone-gel-filled implants. Saline implants have a silicone elastomer shell filled with sterile saline liquid. Silicone gel implants have a silicone shell filled with a viscous silicone gel. There have been several alternative types of breast implants developed, such as polypropylene string or soy oil, but these are uncommon.

Patients seeking breast augmentation have been reported as being usually younger, healthier, from higher socio-economic status, and more often married with children than the population at large.[5] Many of these patients have reported greater distress about their appearance in a variety of situations, and have endured teasing about their appearance. Studies have identified a pattern (shared by many cosmetic surgery procedures) that suggest women who undergo breast implantation are slightly more likely to have undergone psychotherapy, have low levels of self-esteem, and have higher prevalences of depression, suicide attempts, and mental illness (including body dysmorphia[6]) as compared to the general population.[7] Post-operative surveys on mental health and quality of life issues have reported improvement on a number of dimensions including: physical health, physical appearance, social life, self confidence, self esteem, and sexual function.[8][9][10][11] Longer term follow-up suggests these improvements may be transitory, with the exception of body esteem related to sexual attractiveness.[12] Most patients report being satisfied long-term with their implants even when they have required re-operation for complications or aesthetic reasons.[

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Yohimbe and other sexual enhancement medications

Version 5.1, June 2003 (rev.)

Sometime in the future, it will be possible through genetic engineering to create humans who are predisposed to live hundreds, and even thousands, of years, or, in fact, indefinitely. Furthermore, it will be possible not only to engineer new lives predisposed to live indefinitely but also to re-engineer existing human life to live on and on. Existing humans will "infect" themselves with virus-like agents that will carry new genetic information into the nucleus of cells to get rid of diseases, and the aging process.

Procreation will be replaced by re-creation.

Alas, we are not quite there yet. And I myself am not optimistic that I will benefit from the advances in genetic science and become one of the individual humans living on indefinitely. Too sad. I have been born some 100 or 200 or 500 years too early.

Nevertheless, I shall attempt to get the most out of my live, and to go a distance as far as possible, in a condition as good as possible. And this means: in a condition that allows me to enjoy sex as much as possible, and up to the time of my hopefully gentle death.

For optimal sexual function, plain healthy living alone doesn't do the job. This is one thing I know very well. Without sexual enhancement medications, many aging men are not usually in a physical condition that would allow them a fulfilling sex life. And because improvements of sexual function by genetic engineering are currently not available, they largely have to rely on pharmacological means.

I myself have been successful in improving sexual function only with 4 classes of medications:

1. Phosphodiesterase inhibitors such as sildenafil citrate and tadalafil.

2. Dopaminergics such as Parlodel (bromocriptine) and Dostinex (cabergoline).

3. Tongkat ali and tongkat ali extract.

4. Yohimbe (the bark) and yohimbine (the pharmaceutical).

I have been using yohimbine for years (before I switched to tongkat ali), and it definitely worked for erections. But I have long stopped taking it because of the severe side effects it has on me, such as heart palpitations and insomnia for up to 30 hours. For those who do not suffer from these side effects, yohimbe and yohimbine may well be superior to phosphodiesterase inhibitors. While I have found, rather accidentally, a medication that does permit me to go to sleep on yohimbe (see the member section for details), I achieve just as good results with a combination of phosphodiesterase inhibitors and tongkat ali. I have had some initial good results with phosphodiesterase inhibitors and dopaminergics, but they only work for a few times and are no long-term solution. While in many countries of the world (especially Third World countries), phosphodiesterase inhibitors and dopaminergics can be purchased at any pharmacy, those living in the United States face strict restrictions and possible lengthy prison terms obtaining them if possessing these medications without a physician's prescriptions. This is just one aspect that indicates that in spite of the historic pride the US takes in being the so-called Land of the Free, it now is the home of people whose personal freedom is, in many aspects, more severely curtailed than of people in any other part of the world. The need for a physician's prescription anyway is a farce (or is it a money-making scheme for physicians), as anyone who is willing to spend the time for a visit to a clinic and to pay a doctor's fee (or attempt it twice or trice) will obtain the prescriptions. All it takes is to make up a story that fits the drugs' indications.

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Lipectomy

Is a cosmetic surgery operation that removes fat from many different sites on the human body. Areas affected can range from the abdomen, thighs, buttocks, to the neck, backs of the arms and elsewhere. The fat is usually removed via a cannula (a hollow tube) and aspirator (a suction device).

Liposuction is not a low-effort alternative to exercise and diet. It is a form of body contouring with significant attendant risks[1] and is not a weight loss method. The amount of fat removed varies by doctor, method, and patient, but the average amount is typically less than 10 pounds (5 kg).

There are several factors that limit the amount of fat that can be safely removed in one session. Ultimately, the operating physician and the patient make the decision. There are negative aspects to removing too much fat. Unusual "lumpiness" and/or "dents" in the skin can be seen in those patients "over-suctioned". The more fat removed the higher the surgical risk.

As shown previously, reports of people removing 50 pounds (22.7 kg) of fat are exaggerated. However, the contouring possible with liposuction may cause the appearance of weight loss to be greater than the actual amount of fat removed. The procedure may be performed under general or local ("tumescent") anesthesia. The safety of the technique relates not only to the amount of tissue removed, but to the choice of anesthetic and the patient's overall health. It is ideal for the patient to be as fit as possible before the procedure and to have given up smoking for several months.

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Family and environmental factors of drug addiction among young recruits

Jedrzejczak M

Jedrzejczak M Institute of Pedagogics and Health Sciences, Swiçtokrzyska Academy, Kielce, Poland. Drug addiction in a family results from three factors: (1) effect of pathological families on young people's behavior, (2) easy access to drugs, and (3) influence of groups of people of the same age. In the present study, it was investigated to what extent individual factors related to family and environment affect the extent of drug addiction among recruits. The study included 559 subjects. The results proved direct interdependence between the family condition and the extent of narcomania. Drug addicts came mostly from incomplete and pathological families. The main family factors of drug addiction, according to the results obtained, are family atmosphere, strength of family ties, sense of family happiness, structure of authority in the family, and alcoholism. In families where there is warmth and love, children do not or rarely take drugs. Drug addicts come from families where there is ill will and hostility (p < 0.05). Drug addicts have weaker family ties than do those who do not take drugs (w2 = 0.26, p < 0.05). In families where there was contact with drugs, authority belonged to the mother to a greater degree (54.4%) than to the father (23.6%). In 46.3% of the studied drug addicts' families, alcohol was drunk. The results of the investigations approximate results of other studies conducted among young people in Poland and elsewhere in the world.

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[Needs satisfaction deficit among cocaine and/or marijuana users asking for treatment]

García-Aurrecoechea R, Díaz-Guerrero R, Medina-Mora ME

Departamento de Investigación Clínica y Epidemiológica, Centros de Integración Juvenil, Colonia Condesa, México D F. raurre@hotmail.com

As part of a pioneer investigation line on the field of addiction and mental health centred on the operationalization of clinical implications of the motivational theory of Maslow (1954/1970) and feedback treatment and prevention strategies of drug use and its associated disturbances, it is tested the psycho-pathogenesis construct of this theory by means of a cross sectional design of four independent samples, on which it is explored the satisfaction degree of 16 deficitary needs on intentional samples of adolescents and young adults: Three samples of actual users of marihuana (n = 47), cocaine (n = 47) and both substances (n = 50), that were gotten between treatment solicitors and a sample of students and workers non illicit drug users (n = 150).The comparative and predictive statistical analysis provide validity to the psycho-pathogenesis construct of the theory of motivation of Maslow, and its stand out: 1)The potential utility for the treatment of the development of techniques and instruments oriented to cover the deficit of satisfaction of the needs of health, tranquillity, order, emotional security, family justice, love, friendship, respect, tenderness, power, domination, success and money and; 2) The importance for the prevention of the actual consumption of drugs as cocaine or marihuana of the development of strategies focused to keep satisfied the needs of health, tranquillity, affection, respect and success.

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Pseudolarix amabilis

Is a monotypic genus in the family Pinaceae. The sole species, Pseudolarix amabilis is commonly known as Golden Larch, though it is not a true larch (Larix), being more closely related to Keteleeria, Abies and Cedrus. It is native to eastern China, occurring in small areas in the mountains of southern Anhui, Zhejiang, Fujian, Jiangxi, Hunan, Hubei and eastern Sichuan, at altitudes of 100-1500 m. Golden Larch is sometimes known under an old scientific name Pseudolarix kaempferi, but this may cause confusion with Larix kaempferi, the Japanese Larch.

It is a deciduous tree reaching 30-40 m tall, with a broad conic crown. The shoots are dimorphic, with long shoots and short shoots similar to a larch, though the short shoots are not so markedly short, lengthening about 5 mm annually. The leaves are bright green, 3-6 cm long and 2-3 mm broad, with two glaucous stomatal bands on the underside; they turn a brilliant golden yellow before falling in the autumn, whence the common name. The leaves are arranged spirally, widely spaced on long shoots, and in a dense whorl on the short shoots.

The cones are distinctive, superficially resembling a small globe artichoke, 4-7 cm long and 4-6 cm broad, with pointed triangular scales; they mature about 7 months after pollination, when (like fir and cedar cones) they disintegrate to release the winged seeds. The male cones, as in Keteleeria, are produced in umbels of several together in one bud.